δ-CRYSTALLINE FORM OF ARGININE SALT OF PERINDOPRIL, PREPARATION PROCESS THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a crystalline form and a preparation method of perindopril arginine excellent in safety from the viewpoint of pharmaceutical value thereof.SOLUTION: There are provided a δ-crystalline form of an arginine salt of perindopril, its preparation process, and pharmaceutical composition containing the same. The crystalline form is represented by formula (I), and exhibits a characteristic powder X-ray diffraction as measured by a diffractometer having an anticathode of copper.