发明名称 |
METHOD FOR PRODUCING INSULIN ANALOGS HAVING A DIBASIC B CHAIN TERMINUS |
摘要 |
<p>The invention relates to a method for producing a type of insulin by genetically engineering a precursor thereof and converting said precursor to the respective insulin in an enzyme-catalyzed ligation reaction with lysine amide or arginine amide, or by lysine or arginine which is modified by protective groups, and optionally subsequent hydrolysis.</p> |
申请公布号 |
PT2041170(E) |
申请公布日期 |
2013.07.18 |
申请号 |
PT20070785903T |
申请日期 |
2007.07.05 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
FRANK ZOCHER;PAUL HABERMANN |
分类号 |
C07K14/62;C12P21/02 |
主分类号 |
C07K14/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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