发明名称 |
THE METHODS FOR DETECTING MOLECULAR INTERACTIONS |
摘要 |
<p>The present invention relates to methods for dynamically detecting the interactions between various materials including bioactive molecules and for detecting target molecules. More specifically, the present invention relates to a method for dynamically detecting bait-prey interactions and a method for easily detecting target molecules which blocks or activates the interactions, the method comprising: allowing a material capable of forming a nano-assembly matrix, a bait and a prey to interact with each other, and analyzing whether a nano-assembly matrix is formed by the interaction between the bait and the prey in vitro or in vivo; or allowing a material capable of forming a nano-assembly matrix, a bait and a prey to interact with each other, inducing the formation of a nano-assembly matrix by a mediator (regulator) material in vitro or in vivo, and then analyzing whether the prey and the bait co-localizes on the nano-assembly matrix.</p> |
申请公布号 |
EP2179287(B1) |
申请公布日期 |
2013.07.17 |
申请号 |
EP20080793275 |
申请日期 |
2008.08.14 |
申请人 |
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KIM, TAE KOOK;LEE, SEUNG GOO;LEE, SANG KYU;LEE, KYOUNG HU;HA, JAE-SEOK |
分类号 |
G01N33/53;G01N33/50;G01N33/536;G01N33/543;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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