THIAZOLE COMPOUNDS AS PROTIEN KINASE B (PKB) INHIBITORS

摘要

THE INVENTION RELATES TO THIAZOLE COMPOUNDS OF FORMULA I AND FORMULA II AND COMPOSITIONS THEREOF USEFUL FOR TREATING DISEASES MEDIATED BY PROTEIN KINASE B (PKB) WHERE THE VARIABLES HAVE THE DEFINITIONS PROVIDED HEREIN. THE INVENTION ALSO RELATES TO THE THERAPEUTIC USE OF SUCH THIAZOLE COMPOUNDS AND COMPOSITIONS THEREOF IN TREATING DISEASE STATES ASSOCIATED WITH ABNORMAL CELL GROWTH, CANCER, INFLAMMATION, AND METABOLIC DISORDERS.