发明名称 |
HUMAN SOLUBLE RECEPTORS FOR ADVANCED GLYCATION END PRODUCTS (SRAGE), METHODS OF PREPARING HUMAN SRAGE, AND TREATMENT METHODS USING SRAGE |
摘要 |
<p>The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.</p> |
申请公布号 |
WO2013103688(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
WO2013US20103 |
申请日期 |
2013.01.03 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
LIN, LI;PARK, SUNGHA;WEI, WEN;XIAO, RUI-PING;TALAN, MARK, I.;LAKATTA, EDWARD, G. |
分类号 |
A61K38/17;A61K38/16;A61K47/30;A61K47/48;A61P9/00;A61P29/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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