发明名称 |
DRY POWDER INHALATION DRUG PRODUCTS EXHIBITING MOISTURE CONTROL PROPERTIES AND METHODS OF ADMINISTERING THE SAME |
摘要 |
<p>A drug product comprises a dry powder inhalation device containing one or more pharmaceutical compositions present therein, wherein the one or more pharmaceutical compositions comprise active ingredients (I) 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol, or a salt thereof, and (II) (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)thio]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl 2-furancarboxylate or a solvate thereof; a hygroscopic material; and a package which encompasses the dry powder inhalation device and the hygroscopic material defining an enclosed volume therein; wherein each of the active ingredients (I) and (II) are present in the same or different pharmaceutical compositions, and wherein the enclosed volume within the package exhibits a Relative Humidity of from 20% to 40%.</p> |
申请公布号 |
EP2611423(A1) |
申请公布日期 |
2013.07.10 |
申请号 |
EP20110755043 |
申请日期 |
2011.08.31 |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED |
发明人 |
ASWANIA, OSAMA;JIANG, ZHONG;ROCHE, TREVOR, CHARLES;WHITAKER, MARK |
分类号 |
A61K9/14;A61K31/133;A61K31/137;A61K31/58;A61P11/06 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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