摘要 |
PROBLEM TO BE SOLVED: To provide an expression enhancer of a Sirt1-related gene selected from a group comprising Sirt1, Pgc-1α, Lpin1, Igfbp1 and Ucp2.SOLUTION: It is found that expression of a gene of Sirt1, Pgc-1α, Lpin1, Igfbp1 and Ucp2 is enhanced in the level of mRNA expression and/or protein expression, by administration of black vinegar produced from rice, malt and water, or a composition containing a component derived from black vinegar as an effective component. |