摘要 |
PROBLEM TO BE SOLVED: To provide methods, systems and apparatuses for producing delivery devices, preferably the delivery device for oral intake of an agent.SOLUTION: In the broadest aspect, the method comprises: a step of assembling one or more layers comprising one or more materials with an agent or an agent-releasing formulation to form an integrated, preferably laminated device; a step of folding the integrated delivery device to form a folded integrated delivery device; and a step of at least partially enclosing the folded delivery device to a form suitable for oral delivery. Preferably, the integrated device comprises: a first external layer of a first material; a frame of a second material mounted on the first external layer; an agent-releasing formulation housed within the frame; and a second external layer of the first material mounted on the frame. |