The present invention relates to treating a hematologic cancer using a Hypoxia-Inducible Factor (HIF inhibitor). The invention also relates to inducing acute myeloid leukemia remission using the HIF inhibitor. The invention further relates to inhibiting a maintenance or survival function of a cancer stem cell (CSC) using the HIF inhibitor.
申请公布号
EP2506840(A4)
申请公布日期
2013.07.03
申请号
EP20100834883
申请日期
2010.06.25
申请人
ONCOIMMUNE INC.;SUNVITA THERAPEUTICS, LLC.
发明人
LIU, YANG;WANG, YIN;LIU, YAN;MALEK, SAMI N.;ZENG, PAN