Combination therapy against cancer utilising 3-beta-cholestanyl-3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-beta-D-galactopyranoside and is derivatives

摘要

595615 Disclosed is the use of a cholestanol derivative represented by formula (I): wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-; or a cyclodextrin inclusion compound thereof, and an anti-cancer agent (such as a metabolism antagonist, a taxane, a platinum complex, a plant alkaloid, or an alkylating agent; including compounds such as pemetrexed compound, 5-fluorouraciI, Paclitaxel, Docetaxcel, Alimta, Cisplatin, Oxaliplatin or Cyclophosphamide) in independent and separate doses formulated for separate or simultaneous combined administration, wherein said anti-cancer agent is not lidocaine or procaine, in a kit for the preparation of a medicament for the treatment of cancer.