发明名称 |
Use of amide indole derivatives as modulators of ATP-binding cassette transporters |
摘要 |
ABSTRACT - 596889 Disclosed herein is a use of a compound of formula (Id) e.g. 1-(Benzo[d][1,3]dioxol-5-yl)-N-(2-(2-methyl-4-(1H-tetrazol-5-yl)butan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide or a pharmaceutically acceptable salt thereof for treating or lessening the severity of male infertility or pancreatic insufficiency, wherein the variables R1, R2, A, B and n shown in formula (Id) are as defined in the specification. |
申请公布号 |
NZ596889(A) |
申请公布日期 |
2013.06.28 |
申请号 |
NZ20070596889 |
申请日期 |
2007.04.09 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
NUMA, MEHDI MICHEL JAMEL;GROOTENHUIS, PETER D |
分类号 |
C07D405/14;A61K31/404;A61P31/00;C07D405/12 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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