发明名称 |
Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
摘要 |
<p>An inhalable unit dose liquid formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueóus solution or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of corticosteroid, such as budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus. The formulation is prepared by mixing SAE-CD, in solid or liquid (dissolved) form, with an inhalable suspension-based unit dose formulation.</p> |
申请公布号 |
IL225946(D0) |
申请公布日期 |
2013.06.27 |
申请号 |
IL20130225946 |
申请日期 |
2013.04.25 |
申请人 |
CYDEX PHARMACEUTICALS INC. |
发明人 |
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分类号 |
A61K;A61K9/00;A61K9/08;A61K9/12;A61K9/14;A61K31/16;A61K31/57;A61K31/715;A61K47/40;A61K47/48;C08B37/16 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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