发明名称 |
Transfusion preparation |
摘要 |
The invention addresses the problem of providing a transfusion preparation, wherein: Maillard reactions due to reducing sugars and amino acids do not occur during storage; fat droplet size in the fat emulsion does not increase during storage; there is little danger of the patient developing hyperkalemia or experiencing vascular pain or phlebitis even when only one of the transfusion solutions is given; and multiple kinds of vitamins can be blended stably despite being a two-chambered container preparation. The invention provides a transfusion preparation having two chambers that are separated by a partition that can be opened, wherein: a first chamber transfusion solution containing a sugar and a fat emulsion is accommodated in a first chamber; a second chamber transfusion solution containing amino acids and electrolytes is accommodated in a second chamber; the first chamber transfusion solution contains substantially no potassium and has an osmotic pressure ratio of 2.0-3.0; for the second chamber transfusion solution, the potassium concentration is 40 mEq/L or less and the osmotic pressure ratio is 2.5-3.5; and the potassium concentration of the mixture of the first chamber transfusion solution with the second chamber transfusion solution when the partition is opened is 16 mEq/L or more. |
申请公布号 |
AU2011337781(A1) |
申请公布日期 |
2013.06.27 |
申请号 |
AU20110337781 |
申请日期 |
2011.11.28 |
申请人 |
OTSUKA PHARMACEUTICAL FACTORY, INC. |
发明人 |
TANI, SEIJI;MITSUMOTO, YASUHIRO |
分类号 |
A61K9/08;A61K9/107;A61K31/07;A61K31/122;A61K31/198;A61K31/215;A61K31/355;A61K31/375;A61K31/4415;A61K31/519;A61K31/593;A61K31/7004;A61K31/702;A61K31/714;A61P7/08 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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