Microfluidic system with metered fluid loading system for microfluidic device

摘要

A microfluidic system includes a microfluidic device; and a metered fluid loading system formed integrally with the microfluidic device and configured to load a discrete metered volume of fluid into the microfluidic device upon actuation. The figure illustrates a first stage of the fluid input process where the fluid 8 substantially resides in the input channel 48 of the reservoir 46. When the fluid input mechanism 50 is activated the fluid 8 is forcibly injected into the gap between top substrate 36 and lower substrate 44. In a final stage a droplet 10 of the fluid 8 is drawn off from the main body of the fluid 8 by application of appropriate voltages on the electrode array 42 by virtue of the EWOD droplet control mechanism.