发明名称 |
PROCESS FOR CONJUGATION OF NHS ESTERS WITH OLIGONUCLEOTIDES |
摘要 |
The present invention provides processes for the conjugation of NHS esters to amino-modified oligonucleotides. The processes provide the amino-modified oligonucleotide on a solid support such that conjugation can be carried out under conditions that can accommodate a wide variety of NHS esters and oligonucleotides. |
申请公布号 |
US2013158243(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
US201213719901 |
申请日期 |
2012.12.19 |
申请人 |
BALL ROBERT WILLIAM;SIGMA-ALDRICH CO. LLC |
发明人 |
BALL ROBERT WILLIAM |
分类号 |
C07H1/00 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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