发明名称 |
FLUORINE-18 AND CARBON-11 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR LRRK2 |
摘要 |
A method for positron emission tomography (PET) imaging of LRRK2 in tissue of a subject, the method comprising: administering a compound of formula I, formula II or formula III, or a pharmaceutically acceptable salt thereof to the subject, wherein the compound includes at least one C11 or F18 label thereon; allowing the compound to penetrate into the tissue of the subject; and collecting a PET image of the CNS or brain tissue of the subject
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申请公布号 |
US2013156700(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
US201213687441 |
申请日期 |
2012.11.28 |
申请人 |
GENENTECH, INC.;GENENTECH, INC. |
发明人 |
MARIK JAN;SWEENEY ZACHARY KEVIN;CHAN BRYAN K.;ESTRADA ANTHONY |
分类号 |
C07D403/12;C07D239/48 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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