发明名称 |
Crystal forms of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide |
摘要 |
Crystalline polymorphs of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
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申请公布号 |
US8466173(B2) |
申请公布日期 |
2013.06.18 |
申请号 |
US20100831009 |
申请日期 |
2010.07.06 |
申请人 |
LORIMER KEITH;PINES SEEMON H.;BERNHARD PAUL;LITTLER BENJAMIN;HELSINN THERAPEUTICS (U.S.), INC. |
发明人 |
LORIMER KEITH;PINES SEEMON H.;BERNHARD PAUL;LITTLER BENJAMIN |
分类号 |
A61K31/445;C07D401/06 |
主分类号 |
A61K31/445 |
代理机构 |
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