发明名称 |
Labeled Alginate Conjugates for Molecular Imaging Applications |
摘要 |
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.
|
申请公布号 |
US2013149242(A1) |
申请公布日期 |
2013.06.13 |
申请号 |
US201213708306 |
申请日期 |
2012.12.07 |
申请人 |
IKARIA DEVELOPMENT SUBSIDIARY ONE LLC;IKARIA DEVELOPMENT SUBSIDIARY ONE LLC |
发明人 |
RUAN FUQIANG;DECKWERTH THOMAS L.;MEGLASSON MARTIN D. |
分类号 |
C07D255/02;A61K51/06;C07B59/00;C07F1/08;C07F5/00;C08B37/00 |
主分类号 |
C07D255/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|