发明名称 |
METHOD FOR PURIFYING HIGH-PURITY BETULONIC ACID, METHOD FOR PREPARING PIPERAZINE BETULONIC ACID AMIDE DERIVATIVE USING HIGH-PURITY BETULONIC ACID AND DERIVATIVE THEREOF, AND METHOD FOR PURIFYING HIGH-PURITY BOC-LYSINATED BETULONIC ACID USING HIGH-PURITY BETULONIC ACID |
摘要 |
The present invention relates to a method for purifying high-purity betulonic acid, a method for preparing a piperazine betulonic acid amide derivative using high-purity betulonic acid and a derivative thereof, and a method for purifying high-purity Boc-lysinated betulonic acid using high-purity betulonic acid. The present invention relates to a method for purifying high-purity betulonic acid from a product of an organic synthetic reaction between betulin extracted from the bark of a birch and a Jones oxidation reagent, synthesis of piperazine betulonic acid amide derivative using the same, utilization thereof as an antibacterial drug, purification of high-purity Boc-lysinated betulonic acid monomer ester from a product of an organic synthetic reaction between high-purity betulonic acid and lysine, and purification of high-purity Boc-lysinated betulonic acid from a product of hydrolysis of the Boc-lysinated betulonic acid monomer ester. |
申请公布号 |
WO2013002592(A3) |
申请公布日期 |
2013.06.13 |
申请号 |
WO2012KR05154 |
申请日期 |
2012.06.29 |
申请人 |
KOREA INSTITUTE OF ENERGY RESEARCH;CHUE, KUCK-TACK;KIM, TAE-HWAN;TEN, LEONID |
发明人 |
CHUE, KUCK-TACK;KIM, TAE-HWAN;TEN, LEONID |
分类号 |
C07J3/00;C07D295/033;C07D401/04;C07J5/00 |
主分类号 |
C07J3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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