Antigen-specific, tolerance-inducing microparticles and uses thereof
摘要
The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.
申请公布号
AU2011316777(A1)
申请公布日期
2013.06.13
申请号
AU20110316777
申请日期
2011.10.24
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
发明人
KESELOWSKY, BENJAMIN GEORGE;LEWIS, JAMAL;ACHARYA, ABHINAV;CLARE-SALZLER, MICHAEL J.;ATKINSON, MARK A.;WASSERFALL, CLIVE HENRY;XIA, CHANG QING;BRUSKO, TODD M.