发明名称 N-DEMETHYLATION OF 6-KETO MORPHINANS
摘要 <p>The present invention provides processes for the demethylation of an N-methyl morphinan comprising a ketone functional group. In particular, the invention provides methods for the protection of the ketone functional group such that impurities are not generated during the demethylation of the N-methyl morphinan.</p>
申请公布号 EP2601196(A1) 申请公布日期 2013.06.12
申请号 EP20110746372 申请日期 2011.08.03
申请人 MALLINCKRODT LLC 发明人 WANG, PETER, X.;JIANG, TAO;BERBERICH, DAVID, W.;LIAO, SUBO
分类号 C07D489/08 主分类号 C07D489/08
代理机构 代理人
主权项
地址