发明名称 |
METHODS AND COMPOSITIONS FOR DETECTING GENETIC MATERIAL |
摘要 |
This invention provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some cases, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g., blood, plasma). The methods and materials described apply techniques for allowing detection of small, but statistically significant, differences in polynucleotide copy number. |
申请公布号 |
EP2504448(A4) |
申请公布日期 |
2013.06.05 |
申请号 |
EP20100833991 |
申请日期 |
2010.11.25 |
申请人 |
BIO-RAD LABORATORIES, INC. |
发明人 |
HINDSON, BENJAMIN;SAXONOV, SERGE;BELGRADER, PHILIP;NESS, KEVIN;LUCERO, MICHAEL;COLSTON, BILLY |
分类号 |
C12P19/34 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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