发明名称 |
HIV-1 fusion inhibitors and methods |
摘要 |
A new series of HIV-1 fusion inhibitors and methods of use are disclosed. The compounds are based on a substituted indole, benzimidazole, indoline or isoindoline fragment. The compounds find use in inhibiting or preventing HIV fusion from occurring, thus inhibiting or preventing entry of viral RNA into host cells. The compounds may be useful towards other biological targets involving protein-protein interactions.
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申请公布号 |
US8455516(B2) |
申请公布日期 |
2013.06.04 |
申请号 |
US201113006716 |
申请日期 |
2011.01.14 |
申请人 |
GOCHIN MIRIAM;ZHOU GUANGYAN;TOURO UNIVERSITY |
发明人 |
GOCHIN MIRIAM;ZHOU GUANGYAN |
分类号 |
A61K31/47;A61K31/404;C07D209/04;C07D215/00 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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