发明名称 Crystalline forms of ( S ) - 2 - amino - 3 - (4 - ( 2 - amino - 6 - ( (R) - 1 - (4 - ch loro-2- (3 -methyl- 1H- pyrazol- 1 -yl) phenyl) - 2, 2, 2 - trifluoroethoxy) pyrimidin- 4 - yl) phenyl) propanoic acid
摘要 Crystalline forms of (S) - 2 -amino- 3 - (4 - (2 -amino- 6 - ( (R) - 1 - (4 - chloro- 2 - (3 -methyl - lH-pyrazol - 1 -yl) phenyl) - 2, 2, 2 - trifluoroethoxy) pyrimidin - 4 -yl) phenyl) propanoic acid and salts thereof are disclosed. Pharmaceutical dosage forms and methods of their use are also disclosed.
申请公布号 AU2011323302(A1) 申请公布日期 2013.05.30
申请号 AU20110323302 申请日期 2011.11.03
申请人 LEXICON PHARMACEUTICALS, INC. 发明人 LI, QUN;HU, WEIFENG;YANG, XIAOGEN;ZHAO, JIANGQIONG;ZHAO, MATTHEW MANGZHU
分类号 C07D403/12;A61K31/506;A61P1/00;A61P35/00 主分类号 C07D403/12
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