| 发明名称 |
Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer |
| 摘要 |
<p>An isolated molecule which comprises an antibody specifically bindable with a binding affinity below 20 nanomolar, preferably below 10 nanomolar, to a human major histocompatibility complex (MHC) class I being complexed with a HLA-restricted antigen and optionally further comprises an identifiable or therapeutic moiety conjugated to the antibody.</p> |
| 申请公布号 |
EP2329814(B1) |
申请公布日期 |
2013.05.29 |
| 申请号 |
EP20100011766 |
申请日期 |
2003.02.11 |
| 申请人 |
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. |
发明人 |
REITER, YORAM;DENKBERG, GALIT |
| 分类号 |
A61K39/395;G01N33/53;A61K47/48;A61P31/12;A61P37/02;C07K7/06;C07K16/00;C07K16/18;C07K16/28;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;G01N33/569;G01N33/574 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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| 主权项 |
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