发明名称 |
PDX1 expressing endoderm |
摘要 |
Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed. |
申请公布号 |
EP2377922(A3) |
申请公布日期 |
2013.05.29 |
申请号 |
EP20100012385 |
申请日期 |
2005.04.26 |
申请人 |
VIACYTE, INC. |
发明人 |
D'AMOUR, KEVIN ALLEN;AGULNICK, ALAN D.;ELIAZER, SUSAN;BAETGE, EMMANUEL E. |
分类号 |
C12N5/071;C07K14/71;C12N5/00;C12N5/073;C12N5/0735;C12Q1/68 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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