发明名称 |
Long-acting growth hormone and methods of producing same |
摘要 |
Use of a growth hormone protein and polynucleotides encoding same comprising an amino-terminal carboxy-terminal peptide (CTP) of chorionic gonadotrophin and two carboxy-terminal chorionic gonadotrophin CTPs attached to the growth hormone in methods of inducing growth or weight gain, method of increasing insulin-like growth factor (IGF-1) levels, and methods of reducing the dosing frequency of a growth hormone in a human subject are disclosed. Pharmaceutical compositions comprising the growth hormone and polynucleotides encoding the growth hormone of the invention and methods of using same are also disclosed.
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申请公布号 |
US8450269(B2) |
申请公布日期 |
2013.05.28 |
申请号 |
US201113195931 |
申请日期 |
2011.08.02 |
申请人 |
FARES FUAD;FIMA UDI EYAL;PROLOR BIOTECH LTD. |
发明人 |
FARES FUAD;FIMA UDI EYAL |
分类号 |
A61K38/27;A61K38/24;C07K14/59;C07K14/61 |
主分类号 |
A61K38/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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