| 发明名称 |
Compounds for the treatment of inflammatory diseases |
| 摘要 |
This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-alpha combinations thereof.
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| 申请公布号 |
US8450355(B2) |
申请公布日期 |
2013.05.28 |
| 申请号 |
US200913120730 |
申请日期 |
2009.09.22 |
| 申请人 |
WONG MICHAEL K. C.;YU WENSHENG;TONG LING;LAVEY BRIAN J.;SHANKAR BANDARPALLE B.;KOZLOWSKI JOSEPH A.;KIM SEONG HEON;ZHOU GUOWEI;YANG DE-YI;RIZVI RAZIA K.;CHEN LEI;KOSINZKI ANETA MARIA;ROSNER KRISTIN E.;FIRE LUKE;RICHARD JUDSON E.;LI DANSU;MERCK SHARP & DOHME CORP. |
发明人 |
WONG MICHAEL K. C.;YU WENSHENG;TONG LING;LAVEY BRIAN J.;SHANKAR BANDARPALLE B.;KOZLOWSKI JOSEPH A.;KIM SEONG HEON;ZHOU GUOWEI;YANG DE-YI;RIZVI RAZIA K.;CHEN LEI;KOSINZKI ANETA MARIA;ROSNER KRISTIN E.;FIRE LUKE;RICHARD JUDSON E.;LI DANSU |
| 分类号 |
A61K31/4166;A61K31/4178;C07D233/02 |
主分类号 |
A61K31/4166 |
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