发明名称 |
METRONIDAZOLE RESISTANCE IN TRICHOMONAS VAGINALIS AND SINGLE NUCLEOTIDE POLYMORPHISMS |
摘要 |
The present invention is directed to the discovery of single nucleotide polymorphisms (SNPs) in the presence of metronidazole-resistant Trichomonas vaginalis. The presence of G76C, C213G, or C318A (SNP) in tvntr 4 or the presence of A238T, G427C, or T476C (SNP) in tvntr6 provides a reliable biomarker for the presence of metronidazole-resistant Trichomonas vaginalis. The present invention further provides reagents used for detecting the SNPs to screen subjects for metronidazole resistance in Trichomonas vaginalis.
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申请公布号 |
US2013130253(A1) |
申请公布日期 |
2013.05.23 |
申请号 |
US201213680553 |
申请日期 |
2012.11.19 |
申请人 |
MEDICAL DIAGNOSTIC LABORATORIES, LLC;MEDICAL DIAGNOSTIC LABORATORIES, LLC |
发明人 |
HILBERT DAVID W.;GYGAX SCOTT E.;ADELSON MARTIN E.;MORDECHAI ELI;SCHUYLER JESSICA;PAULISH-MILLER TERESA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
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