| 发明名称 |
Promoters exhibiting endothelial cell specificity and methods of using same |
| 摘要 |
<p>The present invention concerns an isolated polynucleotide comprising:
(a) a promoter functional in endothelial cells;
(b) a regulatory element comprising at least one copy of the sequence set forth in SEQ ID NO:8 operably linked to said promoter, and
(c) a nucleic acid sequence encoding a cell toxin under regulatory control of said regulatory element.</p> |
| 申请公布号 |
EP2186530(B1) |
申请公布日期 |
2013.05.22 |
| 申请号 |
EP20090174998 |
申请日期 |
2001.11.15 |
| 申请人 |
VASCULAR BIOGENICS LTD. |
发明人 |
HARATS, DROR;BLOOM, NIRA |
| 分类号 |
A61K48/00;C12N15/09;A61K31/7088;A61K45/06;A61P9/00;A61P17/00;A61P35/00;A61P43/00;C07K14/475;C07K14/515;C07K14/575;C12N5/10;C12N15/85 |
主分类号 |
A61K48/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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