发明名称 ANTI-ADDL MONOCLONAL ANTIBODY AND USES THEREOF
摘要 <p>This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils and, optionally, a tau therapeutic or an inhibitor of amyloid beta production or aggregation.</p>
申请公布号 EP2593475(A2) 申请公布日期 2013.05.22
申请号 EP20110807457 申请日期 2011.07.13
申请人 MERCK SHARP & DOHME CORP. 发明人 GASPAR, RENEE C.;SHUGHRUE, PAUL J.;WANG, FUBAO;WANG, WEIRONG;ZHANG, NINGYAN;ZHAO, WEI-QIN;MCCAMPBELL, ALEXANDER;XU, MIN
分类号 C07K16/18;A61K39/395;A61P25/28 主分类号 C07K16/18
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