发明名称 |
ANTI-ADDL MONOCLONAL ANTIBODY AND USES THEREOF |
摘要 |
<p>This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils and, optionally, a tau therapeutic or an inhibitor of amyloid beta production or aggregation.</p> |
申请公布号 |
EP2593475(A2) |
申请公布日期 |
2013.05.22 |
申请号 |
EP20110807457 |
申请日期 |
2011.07.13 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
GASPAR, RENEE C.;SHUGHRUE, PAUL J.;WANG, FUBAO;WANG, WEIRONG;ZHANG, NINGYAN;ZHAO, WEI-QIN;MCCAMPBELL, ALEXANDER;XU, MIN |
分类号 |
C07K16/18;A61K39/395;A61P25/28 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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