| 发明名称 |
TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS BY INHIBITION OF BLIMP-1 |
| 摘要 |
The present invention provides methods of treating autoimmune and inflammatory disorders by inhibition of Blimp-1 activity, and methods of screening for antagonists of Blimp-1 for use in such methods of treatment. Also provided are methods of enhancing Th17 immune response, and methods of screening for agonists of Blimp-1 for use in such methods of enhancing Th17 immune responses. |
| 申请公布号 |
WO2013070563(A1) |
申请公布日期 |
2013.05.16 |
| 申请号 |
WO2012US63635 |
申请日期 |
2012.11.06 |
| 申请人 |
MERCK SHARP & DOHME CORP.;JAIN, RENU;CUA, DANIEL, J. |
发明人 |
JAIN, RENU;CUA, DANIEL, J. |
| 分类号 |
C12N15/00;C12N5/07;C12N5/10 |
主分类号 |
C12N15/00 |
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