The present invention relates to B-domain truncated Factor VIII molecules with a modified circulatory half life, said molecule being covalently conjugated with a hydrophilic polymer. The invention furthermore relates to methods for obtaining such molecules as well as use of such molecules.
申请公布号
AU2013204960(A1)
申请公布日期
2013.05.16
申请号
AU20130204960
申请日期
2013.04.12
申请人
NOVO NORDISK A/S
发明人
DEFREES, SHAWN;BOLT, GERT;THIM, LARS;VANDAHL, BRIAN BERG STIDSEN;STENNICKE, HENNING RALF;STEENSTRUP, THOMAS DOCK
