发明名称 |
Sulfonamide compounds or salts thereof |
摘要 |
Disclosed is a compound useful as an EP1 receptor antagonist. Studies are made on EP1 receptor antagonists, and it is confirmed that a compound having a sulfonamide structure in which a nitrogen atom in the sulfonamide structure is substituted by a 2-fluoropropyl group, a 3-fluoro-2-methylpropyl group or the like has a potent antagonistic activity on an EP1 receptor. The sulfonamide compound has a potent antagonistic activity on an EP1 receptor and therefore can be used as a prophylactic and/or therapeutic agent for a lower urinary tract symptom or the like. |
申请公布号 |
AU2009263457(B2) |
申请公布日期 |
2013.05.16 |
申请号 |
AU20090263457 |
申请日期 |
2009.06.22 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
TSUKAMOTO, ISSEI;KATO, KOJI;AZAMI, HIDENORI;KAMIJO, KAZUNORI;FUKUDA, YUTA;KUBOTA, HIDEKI |
分类号 |
C07C311/21;A61K31/341;A61K31/426;A61K31/427;A61K31/4402;A61K31/4406;A61K31/443;A61K31/4439;A61K31/497;A61K31/501;A61K31/506;A61P13/02;A61P13/08;A61P13/10;A61P43/00;C07D213/71;C07D277/20;C07D277/36;C07D277/56;C07D307/64;C07D405/12;C07D417/12;C07K14/705 |
主分类号 |
C07C311/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|