发明名称 |
Upregulation of integrin linked kinase (ILK) to provide cardioprotective effects |
摘要 |
Modulation of the integrin-linked kinase (ILK) signaling pathway is used to enhance the remodeling process relevant to a wide range of cardiac diseases. More specifically, a process to instigate beneficial human cardiac hypertrophy or for post myocardial infraction (MI) remodeling comprising illiciting an overexpression of ILK, is described. The ILK signaling pathway is also used as a means for cardiac stem cell proliferation and self-renewal. |
申请公布号 |
US8440421(B2) |
申请公布日期 |
2013.05.14 |
申请号 |
US201213410358 |
申请日期 |
2012.03.02 |
申请人 |
COLES JOHN G.;HANNIGAN GREGORY;LU HUANZHANG |
发明人 |
COLES JOHN G.;HANNIGAN GREGORY;LU HUANZHANG |
分类号 |
C12Q1/48;C12N5/077 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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