发明名称 |
3-PHENYLPYRAZOLO[5,1-b]THIAZOLE COMPOUND |
摘要 |
Disclosed is a compound represented by formula (I) or a sail thereof, which has an excellent antagonistic activity on a CRF receptor and also has sufficient levels of a pharmacological activity, safely and in vivo kinetics for use as a medicinal agent. [In the formula, Rrepresents a group represented by formula-A-A; Rrepresents a tetrahydrofurylmethyl group, a tetrahydropyranylmethyl group or a tetrahydropyranyl group; Arepresents a single bond, a methylene group or a 1,2-ethylene group; Arepresents a C1-6 alkyl group, a C3-6 cycloalkyl group, or a C3-6 cycloalkyl group having a methyl group; Rrepresents a methoxy group, a cyano group, a cyclobutyloxymethyl group, a methoxymethyl group or an ethoxymethyl group; and Rrepresents a methoxy group or a chlorine atom.](I) |
申请公布号 |
UA101836(C2) |
申请公布日期 |
2013.05.13 |
申请号 |
UA20100013461 |
申请日期 |
2009.04.09 |
申请人 |
EISAI R & D MANAGEMENT CO., LTD. |
发明人 |
SHIBATA, HISASHI;SHIKATA, KODO;INOMATA, AKIRA;SHIN, KOGYOKU;TERAUCHI, TARO;TAKAHASHI, YOSHINORI;HASHIZUME, MINAKO;TAKEDA, KUNITOSHI |
分类号 |
C07D513/04;A61K31/429;A61P9/10;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/30 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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