| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine, particularly to pharmacology, and concerns creating a drug preparation of an active substance of rifabutin by parenteral administration for treating human and animal infectious when administered parenterally. The parenteral drug preparation of rifabutin for therapy for the human and animal infectious diseases containing the active substance of rifabutin, excipients and water for injections, with the excipients presented by sodium metabisulphite and disodium edetate in the following ratio, g per 1 litre of water for injections: rifabutin 20-40, sodium metabisulphite, 0.7-0.9; 0.1-0.3 disodium edetate, water for injections - 1 litre.EFFECT: invention provides a high therapeutic effect and high stability of the drug preparation, reduces the gastrointestinal toxicity of rifabutin, well tolerated, does not cause allergies and other side effects.2 ex |
