发明名称 COMBINATIONS OF MOLECULAR MARKERS IN PROSTATE CANCER PROVIDING A DIAGNOSTIC TOOL WITH IMPROVED SENSITIVITY/SPECIFICITY
摘要 The present invention relates to methods for in vitro establishing, or diagnosing, high grade or low grade prostate cancer in a sample, preferably from a readily obtainable sample such as an urine, a prostatic fluid or ejaculate sample or a processed, or derived sample thereof, originating from human individual suspected of suffering from prostate cancer using expression level analysis of a combination of two, or three molecular markers for prostate cancer selected from DLX1, HOXC6 and HOXD10. The present invention further relates to the use in expression level analysis of these combined markers for in vitro establishing high grade or low grade prostate cancer and to a kit of parts providing expression analysis of combinations of the present molecular markers for establishing high grade or low grade prostate cancer.
申请公布号 WO2013064636(A1) 申请公布日期 2013.05.10
申请号 WO2012EP71727 申请日期 2012.11.02
申请人 NOVIOGENDIX RESEARCH B.V. 发明人 SMIT, FRANCISCUS PETRUS;SCHALKEN, JACK A.;HESSELS, DAPHNE
分类号 C12Q1/68 主分类号 C12Q1/68
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