| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula(1), in which Ar is a group of formula(Ar-1) or(Ar-2), in which Ris a halogen, Ris hydrogen, Ris hydrogen, Ris hydrogen, alkyl or alkenyl, X is a nitrogen atom or CH, Rand Rare each hydrogen and h equals 1; 1 equals 1 or 2; m equals 1 or 2; n equals 0, 1 or 2; o equals an integer from 0 to 3, under the condition that n and o are equal to 0 at the same time. Values of group A are as given in claim 1 of the invention. Described also is a pharmaceutical composition having agonistic activity with respect to 7 serotonin (5-HT-receptors), which contains a compound of formula (1) and an agent which stimulates enterokinesis or improves functioning of the alimentary canal, which contains a compound of formula (1) as an active ingredient.EFFECT: novel compounds are obtained and described, which have strong affinity towards 4 serotonin receptors, which are useful as an agent which stimulates enterokinesis or an agent which improves functioning of the alimentary canal.28 cl, 233 ex, 29 tbl |
