| 发明名称 |
COMPOUND FOR MODULATING TRPV3 FUNCTION |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide methods and compositions that modulate a TRP family member. <P>SOLUTION: The method for treating or preventing a condition involving activation of TRPV3 or for which reduced TRPV3 activity can reduce the severity includes administering a compound in an amount effective to inhibit TRPV3-mediated current with an IC<SB POS="POST">50</SB>of 1 micromolar or less. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2013082755(A) |
申请公布日期 |
2013.05.09 |
| 申请号 |
JP20130023822 |
申请日期 |
2013.02.08 |
| 申请人 |
HYDRA BIOSCIENCES INC |
发明人 |
CHONG JAYHONG A;FANGER CHRISTOPHER;MORAN MAGDALENA M;UNDERWOOD DENNIS JOHN;ZHEN XIAOGUANG;RIPKA AMY;WEIGELE MANFRED;LUMMA WILLIAM C JR;LARSEN GLENN R;MAHADEVAN ANU;MELTZER PETER |
| 分类号 |
A61K45/00;A61K9/10;A61K9/12;A61K31/428;A61K31/4709;A61K31/498;A61K31/5365;A61K31/55;A61K45/06;A61P1/02;A61P1/04;A61P9/14;A61P11/14;A61P13/10;A61P17/00;A61P17/04;A61P17/06;A61P17/14;A61P19/02;A61P25/02;A61P25/06;A61P29/00;A61P29/02;C07D401/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D513/04 |
主分类号 |
A61K45/00 |
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