发明名称 |
Active agent prodrugs with heterocyclic linkers |
摘要 |
<p>The embodiments provide prodrug compounds of Formulae I-XVII. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug compound of Formulae I-XVII that provides controlled release of an active agent. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of an active agent from the prodrug so as to attenuate enzymatic cleavage of the prodrug.</p> |
申请公布号 |
AU2012225337(A1) |
申请公布日期 |
2013.05.09 |
申请号 |
AU20120225337 |
申请日期 |
2012.03.08 |
申请人 |
SIGNATURE THERAPEUTICS, INC. |
发明人 |
JENKINS, THOMAS E.;HUSFELD, CRAIG O. |
分类号 |
A61K38/08 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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