发明名称 METHOD OF DETERMINING THE PROTEASE CATHEPSIN B IN A BIOLOGICAL SAMPLE
摘要 <p>Method of determining the potentially available activity of cathepsin B in a biological sample, including the activity of the active form of cathepsin B, the activable form of cathepsin B from the proform procathepsin B which is present in the sample and the activable form of cathepsin B which is present in the sample in a form in which it is inhibited in respect of its protease activity by protease inhibitor, where procathepsin B present in the sample is converted into the active form cathepsin B, the content of free cathepsin-B-protease inhibitor present in the sample is reduced, or the inhibitor function of free cathepsin-B-protease inhibitor present in the sample is blocked and the protease inhibitor is removed from the inhibited form of cathepsin B, and the activity of the active cathepsin B present in the sample is subsequently determined.</p>
申请公布号 EP2588627(A1) 申请公布日期 2013.05.08
申请号 EP20110730629 申请日期 2011.07.01
申请人 PAPST LICENSING GMBH & CO. KG 发明人 MEIER, HANS JOERG;MAUK, HANNS JOERG
分类号 C12Q1/37 主分类号 C12Q1/37
代理机构 代理人
主权项
地址