| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies. <P>SOLUTION: The compounds have the general formula (I), wherein: ring A is a carbocycle or heterocycle; ring B is a carbocycle or heterocycle; R<SB POS="POST">1</SB>is hydroxyl, halogen, or the like; R<SB POS="POST">2</SB>is halogen, hydroxyl, or the like; R<SB POS="POST">3</SB>is halogen, hydroxyl, or the like; R<SB POS="POST">4</SB>is H or alkyl; R<SB POS="POST">5</SB>is halogen, alkyl or haloalkyl; m is 0-3; and n is 0-4. <P>COPYRIGHT: (C)2013,JPO&INPIT |
