| 发明名称 |
ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 |
| 摘要 |
Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune cell through the PD-1 pathway is also disclosed. |
| 申请公布号 |
US2013109843(A1) |
申请公布日期 |
2013.05.02 |
| 申请号 |
US201213719756 |
申请日期 |
2012.12.19 |
| 申请人 |
MSD OSS B.V.;MDS OSS B.V. |
发明人 |
CARVEN GREGORY JOHN;VAN EENENNEEM HANS;DULOS GRADUS JOHANNES |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
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