| 发明名称 |
PLATINUM COMPOUNDS THAT INHIBIT CONSTITUTIVE STAT3 SIGNALING AND INDUCE CELL CYCLE ARREST AND APOPTOSIS OF MALIGNANT CELLS |
| 摘要 |
The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions. In one embodiment, a compound of the invention has the structure shown in formula I, formula II, or formula III. The subject invention also concerns methods of using the compounds and compositions of the invention. |
| 申请公布号 |
WO2013063504(A1) |
申请公布日期 |
2013.05.02 |
| 申请号 |
WO2012US62272 |
申请日期 |
2012.10.26 |
| 申请人 |
H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC.;UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
SEBTI, SAID, M.;LAWRENCE, NICHOLAS, J.;TURKSON, JAMES |
| 分类号 |
C07F15/00;A61K31/495;C07D241/04 |
主分类号 |
C07F15/00 |
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