发明名称 |
Methods for the synthesis of pyridoxamine |
摘要 |
The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products. |
申请公布号 |
US8431712(B2) |
申请公布日期 |
2013.04.30 |
申请号 |
US20100855108 |
申请日期 |
2010.08.12 |
申请人 |
KHALIFAH RAJA G.;KEILITZ ROLAND;KOELLNER CHRISTOPH;DEGENHARDT THORSTEN;BRAND STEPHEN ROBERT;NEPHROGENEX, INC. |
发明人 |
KHALIFAH RAJA G.;KEILITZ ROLAND;KOELLNER CHRISTOPH;DEGENHARDT THORSTEN;BRAND STEPHEN ROBERT |
分类号 |
C07D213/62;A61K31/4415;C07D213/66;C07D213/67;C07D401/12 |
主分类号 |
C07D213/62 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|