| 发明名称 |
Process for the reductive alkylation of normorphinans |
| 摘要 |
The invention provides a process for the N-alkylation of normorphinan compounds to produce N-alkylated morphinan compounds. In particular, the process relates to the alkylation of a normorphinan compound by a carboxaldehyde in the presence of a reducing agent to form an N-alkylated morphinan. |
| 申请公布号 |
US8431701(B2) |
申请公布日期 |
2013.04.30 |
| 申请号 |
US20100706909 |
申请日期 |
2010.02.17 |
| 申请人 |
HUDSON EDMUND C.;WOODS SHARON;MALLINCKRODT LLC |
发明人 |
HUDSON EDMUND C.;WOODS SHARON |
| 分类号 |
C07D489/00;C07D221/28 |
主分类号 |
C07D489/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
