ANTICANCER COMPOSITION CONTAINIG THE BENZOCHALCONE

摘要

PURPOSE: A benzochalcone compound is provided to suppress the growth of cancer cells by cutting poly ADP-ribose polymerase-1(PARP-1) by activating a caspase enzyme. CONSTITUTION: A manufacturing method of a benzochalcone compound comprises a step of dissolving 2-hydroxy-1-acetonaphthone and 2,4,6-trimethoxybens-aldehyde in an ethanol; a step of adding 50% KOH aqueous solution into the mixture; a step of stirring and cooling the mixture solution; a step of neutralizing the mixture solution by HCl solution; a step of vacuum filtering and washing the benzochalcone compound which is generated during the neutralization; and a step of recrystallizing the washed benzochalcone compound in ethanol.