发明名称 ACTIVATORS OF CLASS I HISTONE DEACETLYASES (HDACS) AND USES THEREOF
摘要 The present invention provides compounds of Formulae (A), (B), (C), and (D), pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof, pharmaceutical compositions thereof, and kits thereof. The present invention further provides methods of using the compounds to treat or prevent neurological disorders. In one aspect, the methods include administering to a subject in need of treatment for a neurological disorder a therapeutically effective amount of DAC-001, DAC-002, DAC-003, DAC-009, or DAC-012, or a compound of Formula (A), (B), (C), or (D).
申请公布号 US2013096129(A1) 申请公布日期 2013.04.18
申请号 US201213554670 申请日期 2012.07.20
申请人 TSAI LI-HUEI;PAN LING;HAGGARTY STEPHEN J.;PATNAIK DEBASIS 发明人 TSAI LI-HUEI;PAN LING;HAGGARTY STEPHEN J.;PATNAIK DEBASIS
分类号 C07C219/28;C07D307/52;C07D405/12;C07D409/12;C07D487/04 主分类号 C07C219/28
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