| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide compositions and methods for modulating the expression of apolipoprotein B. <P>SOLUTION: Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein B. Pharmaceutical compositions and other compositions comprising the compounds are also provided. Methods for modulating the expression of apolipoprotein B in the cells are further provided. <P>COPYRIGHT: (C)2013,JPO&INPIT |
